![]() ![]() The Reference 3912 stopwatch takes a different approach, counting down 10 minutes on a small recorder at the top of the dial and counting down 60 seconds on the outer track. The Reference 33.712 stopwatch counts down 5 minutes on a central minute register, with a 60 second countdown on the outer track. Our review of Heuer’s regatta timers begins in 1959, with a catalog that shows only two stopwatches. Still, a review of the catalogs provides a good overview of the history of these timepieces. We point out that Heuer made certain yacht timers that never appeared in its catalogs. Rather than examining the timepieces themselves, we will review the timepieces that Heuer presented in its catalogs and brochures. ![]() ![]() In this posting, we will survey the yacht timers that Heuer offered over the years from 1959 through 1984. Of course, let’s not forget that the ideal yacht timer must be waterproof and shock resistant. In the minutes before the start of the race, the deck will be a busy place, so simplicity in the design and functions of the watch will also be critical. Bigger will usually be better, especially for the captain reading the countdown to the start of the race. The competitors have a set time before the start of the race (usually 10 minutes), to plot their course / develop their approach to the start line, and the boat that gets to the start line in the best position will be at a significant advantage in the race itself.īouncing on the waves, with the sun and spray obstructing the view, legibility will be critical. First, while timing the race itself is important, the countdown to the start of the race may be even more important. Heuer developed special timepieces for many types of competitions, but yacht races (regattas) presented some unique challenges. Heuer made split second stopwatches to time the differential between two runners, two horses or two cars, flyback timers to check lap times, and even a chess clock will keep track of the times of the players’ moves. The waterski-slalom timer (Reference 403.632) indicates the motorboat’s speed over a measured distance, while the rowing timer (Ref 403.414) shows strokes per minute. Indeed, the parachutist had no need for even the simplest feature, the time-in and time-out button to stop and restart the watch. By contrast, the parachutist had far simpler requirements, being well-served by a simple 60 second stopwatch, that is highly legible and reliable in low temperatures. For example, for track and field, Heuer recommended a stopwatch with 1/100 second indication, with split action (show, below left). Many of Heuer’s stopwatches and chronographs were designed for specific sports. Glancing at Heuer’s 1970 /71 catalog of timers and chronographs, we see timepieces for over 40 sports, ranging from bobsledding to boxing, and from and rodeo to rugby. Although today’s enthusiasts associate Heuer most closely with motorsports, over the years Heuer developed and marketed a vast array of stopwatches and chronographs for timing all sorts of sports events. ![]()
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![]() ![]() Use this simple technique to convert fresh herbs to dried herbs: 1 teaspoon dried herbs for every 1 tablespoon fresh herbs. What is the dried equivalent of 2 tablespoons of fresh basil? However, when substituting dried basil for fresh basil, use less dried basil because dried herbs have a stronger flavor. It’s an excellent fresh basil substitute if you have dried basil. Can I substitute dried basil for fresh basil? Using our 3:1 ratio, we can calculate that 2 tablespoons of dried basil are equivalent to a cup fresh sweet basil. How much is dried basil in a cup of fresh basil? A half-cup contains little over 6 tablespoons. In our guide, you can learn more about working out the amounts to get the basil taste and how you can work out 1/4 cup fresh basil, equals how much dried? How Much Dried Basil Is Equal To A Cup Of Fresh Basil? As this may occur with other herbs, you can use the concepts of dried rosemary, and fresh rosemary or fresh thyme and dried thyme among others for the calculations. (Learn How To Get Sharpie Off Of Pumpkin) fresh basil?” Dry basil to fresh basil equates to around one-third of dried than you would use the herb fresh. So, if your recipe calls for 1 cup of fresh basil, you’ll probably wonder, “How much dried basil vs. Knowing how much fresh herbs compared to dried is vital if you need to use dried rather than fresh. As a result, you end up with a more concentrated flavor. If you don’t have any fresh basil on hand, you can use dried basil insteadīasil contains roughly 85-90 percent water, eliminated during the drying process. You’ll use finely chopped basil in pizza, spaghetti, or with fish, and more. Basil is a widely used herb in cooking, particularly in Italian cuisine. ![]() ![]() It give this soup a little extra kick because of the jalanpeno.
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When we discussed this particular gaming application, we found the gameplay rich with joy and opportunity.Introduction to the builder base with new building’s and unlock some mysteries character. ![]() ![]() I do not have a solid name for these glorious boots, but was thinking of "The Master's Journey".Īs flavour text I was thinking about a mentor teaching a student to "slowly endure harsh lessons, because experience and hard work will never betray you". ![]() Unique Modifier: You cannot be knocked back while at maximum Endurance Charges Unique Modifier: Endurance Charges cannot be stolen or removed while at maximum Endurance Charges Unique Modifier: +1 Maximum Endurance Charges So here is my proposal for a Unique item that would fix this issue, for the few people who care about it and would like to see this band-aid like fix.Ī Unique pair of boots with the following stats Īrmor based boots (I'm thinking Titan Greaves) So I have thought a long time about abandoning the build I have made and perfected for three leagues, but I just can't abandon it without trying to fix this issue for myself and other slow but steady, endurance charge relying build lovers. Simulacrum (when mobs have a chance to remove all charges it is immediatly over).Īrchnemesis' Draught Bringer (removes all charges on hit).ĭelve zone modifier (these zones are just bricked).Īs a Marauder with the Juggernaut ascendancy that encourages the use of endurance charges, it is quite frustrating to have a chance to instantly die when I encounter one of these sources. Maps (scour+alc is a solution here, unless corrupted, then it's just bricked). It tickles my niche perfectly and so I have spend more hours than I'd like to admit on creating a perfect build for it, so far I'm satisfied with the result of the build.īut as a character that relies heavily on endurance charges to survive it pains me greatly that there are sources that completely remove all these endurance charges in a single hit, this modifier is found in multiple instances, such as Three leagues ago I took an interest in the skill gem Boneshatter and have been smitten by it, how it builds stacks, how it deals damage to my character and how it interacts with Mantra of Flames. ![]() ![]() I am an enjoyer of slow but absurdly tanky builds, and have been enjoying Path of Exile's content for a while now on my own slow pace. ![]() ![]() In large sizes, one carat or above, its intense fire may give it away as a non-diamond gem. Moissanite has more than twice the fire of diamond and slightly more brilliance. 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This might be especially important for some molecules that are sensitive to acidic pH values. Third, an elution pH study was performed to find the optimal elution pH. ![]() Performed in small columns with purified protein. The DoE for all steps is outlined in Figure 2.įor the capture step, Capto L was chosen and wide wash and elution conditions were evaluated in a 96-well format using PreDictor plates. This general approach also supports QbD, where the plates give the characterized space and the DoE in columns provides both the design and the control space. Perform capacity studies (column) with purified protein (only binding steps) Choose media and wash or elution conditions by screening in platesĢ. Table 1 shows the properties of the Fab.ĭuring the set-up of this three-step process, a general workflow was used with the purpose of minimizing the development time by using High Throughput Processġ. With its recombinant protein L ligand, Capto L is a BioProcess™ chromatography medium with a broad range affinity for antibody fragments of different sizes containing kappa light chains (Fig 1).Ī three-step Fab purification process using Capto media Here we describe an example of using Capto media in a purification process of a kappa subclass Fab originating from an E. With the introduction of Capto L, the first industrial platform for the purification of antibody fragments is now emerging. Antibody fragments, however, have previously lacked such a platform solution. The high purification factor and generic conditions associated with this approach have proven particularly attractive to biopharmaceutical manufacturers. The industry standard for purifying MAbs is a platform approach using affinity chromatography with protein A as the capture step. One of the advantages is that due to their structure and smaller size, antibody fragments possess properties (e.g., easier tissue penetration) that suit a range of diagnostic and therapeutic applications. This platform approach enables increased efficiency and productivity in developing therapeutics based on antibody fragments.Īntibody fragments (e.g., Fab, scFv, domain antibodies, etc.) are set to become the next important class of proteinbased biotherapeutics after monoclonal antibodies (MAbs). Using Capto™ L, Capto SP ImpRes, and Capto Q media in the three step process resulted in efficient removal of the main contaminants and high yields (≥ 87%) over the entire process. This general approach supports Quality by Design (QbD), where the plates give the characterized space and the DoE in columns render both the design and the control space. Design of Experiments (DoE) was used to further optimize the conditions for each step. Next, capacity studies were performed in small columns with purified protein, and elution studies in columns were performed to find the optimal elution pH. First, chromatography media (resins) were screened in 96-well PreDictor™ plates, using wide wash and elution conditions. This Application note describes a three-step purification process of a Fab originating from an E. ![]() ![]() ![]() Firstly, we must understand, under what circumstances the general institute – regulating international relations and constituting international norms – intends humanitarian intervention and what operations it allows in such cases. However, along with the mentioned principle, we often hear the “humanitarian intervention”concept, which is controversial and raises a number of questions. Well-known principles and goals of the United Nations are the protection of human rights, the right of people’s self-determination, non-use of force in international relations and also non-interference and non-intervention in the internal affairs of the States (Article 2/7). He emphasizes that it is done without the agreement of the target state. McKinley defines intervention as an intentional act of a state, grouping of states or international agency, which aims to influence the internal politics of another country. There is no legal definition for humanitarian intervention, and different authors describe this phenomenon in different ways. And what the humanitarian intervention actually is? What are its goals and motivations? The purpose of this analysis is to understand the nature and objectives of humanitarian intervention, to consider some examples and to draw conclusions, in which case may the interference be considered as “humanitarian” and “justified”. In some cases, when there has indeed been a need to intervene and help the UN and other powerful countries haven’t done anything and many crimes have been made in front of their eyes, such as in Rwanda and Somali. However, there have also been successful interventions, such as the overthrow of the dictatorial regime of Idi Amin in Uganda by Tanzanian armed forces, which had destroyed more than 300.000 citizens of his country. The case of Iraq is not the only one: in recent years, in succession to each other, crisis began in Egypt, Libya, Yemen and other Arabic countries. ![]() In the case of the USA, discontentment appeared in the country, also because of the huge costs that the war demanded: on the Iraq war, the US has spent $ 2 trillion. ![]() However, it is not always that initiatives pursuing such good intentions have a positive effect: it is enough to remember the US-Britain-initiated intervention of coalition forces in Iraq, as a result of which, according to many sources, more than 165 civilians have been killed, not counting the fact, that after that incidents the civil war began in the country, state infrastructures were disturbed and Iraq appeared in a deeper crisis. Nevertheless, the cases of putting troops in any country is being officially explained in such way. Recently, we often hear about the “humanitarian interventions” which are often done to put an end to the violations of human rights or to protect people fighting against dictatorial regimes in such countries. ![]() ![]() So, what is the reason for success of such simple game? Everything is quite simple, and that’s all! Thanks to understandable rules and interface, nice graphics, various versions this games became very popular among gamers of any ages. Try also newest games like: Zuma Deluxe 2, Zuma Totemia, Egypt Zuma, Zuma 3. The level is completed when after the bar is filled, the player eliminates all of the balls on the screen. To eliminate them, the player should connect three or more of the same color balls. As soon as one ball reaches the skull or hole (depends on the version you have chosen), the rest follow and the player loses a life. The player can carry two balls at a time and can switch at any time. The main goal of Zuma is to eliminate all of the balls rolling around the screen along, like a snake. The rules pretty easy and understandable to all in the short period of time. Instead of frog you can find Panda, Scarab beetle, and even Santa, who can throw multi-colored snowballs. In some games instead of balls you can find beads, valuable gems and even glistening pearls. On our pages you will find adventures, look like classical Zuma. On our site you will be able to familiarize yourself with different versions of Zuma Games, such as: Zuma Deluxe, Zuma Maya, Zuma Revenge, Inca Ball and so on. And of course, the variety of versions is always pleasing to the eye. The game can be played by both children and students, adults and old people. Fire magical balls from your stone frog idol to make matches of three or more and clear the deadly chain before it. In addition, the game picture itself has been improved, the colors are much brighter, there are more levels. Survive the ancient temples of Zuma, the critically acclaimed action-puzzler from PopCap Deep in the jungle lie hidden temples bursting with traps and trickery, and its up to you to uncover their treasures. Nowadays, this game has become even more popular than before, because now you can play it at any time on any device for free and without even needing to register. On our site we want to introduce you a lot of different versions of your favorite game: Zuma Revenge 2, Zuma Balls, Marlbes, Zuma Original. Of course you have heard more than once about Zuma game and even have played in it several times, for sure. That all depends on your opportunities and preferences. You can play in this game via your laptop, desktop or even mobile. It refers to a tile-matching puzzle video game, so you obviously will like it even if you haven’t played it before. A lot of levels, clarity of the task - this is what attracts people so much in this seemingly simple but interesting game.Zuma is a computer game which was created in 2003 and had worldwide popularity. These games impressed everyone from the children who are ready to sit in front of the computer for hours playing Zuma, to adults who are bored at home or at work. Zuma Games - play 42 online games for free 3.50 from 10 votes. There is only one the most important criterion by which the games are divided. No matter who the main character is: a frog or any other. Now everyone knows such games as Zuma Deluxe, Revenge, Indian Mystic Zuma, Balls, Blitz or games about the Dolphin or Bongo monkey. The main idea has not changed – a combination of the same items and their destruction. The game is still popular, but now there are many varieties of them. ![]() A lot of time has passed since that time. ![]() These games were popular back in 2005, but there was only one version of the game. With the help of these games you can check your attention, logic skills and your ability to think many moves ahead. New heroes, new obstacles, new playing field and new bonuses are waiting for you! But they’re still the same good old familiar Zuma games! ![]() We're delighted to welcome you on our website dedicated to the Zuma games! Here you can find more than 35 online games, various in design and presentation. Meet the most famous classical casual game Zuma Deluxe is the world of wonderful labyrinths and multicolor balls, which constantly move to their inevitable. ![]() |
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